Journal of the International Association of Providers of AIDS Care (Jan 2018)

Immunologic and Virologic Outcomes of Obese and Nonobese Incarcerated Adults on Antiretroviral Therapy for HIV Infection

  • Kristen L. Bunnell PharmD,
  • Arwa Aldossari PharmD(c),
  • Connor Perkins PharmD(c),
  • Christopher Schriever PharmD,
  • Thomas D. Chiampas PharmD,
  • Jeremy D. Young MD,
  • Mahesh C. Patel MD,
  • Melissa Badowski PharmD, BCPS, AAHIVP

DOI
https://doi.org/10.1177/2325957417752261
Journal volume & issue
Vol. 17

Abstract

Read online

Background: Obesity is common among patients with HIV. The objective of this study was to characterize response to antiretroviral therapy (ART) in a cohort of obese incarcerated adults compared to a nonobese cohort. Methods: A retrospective matched cohort study was conducted in an HIV telemedicine clinic. Patients with body mass index (BMI) >30 kg/m 2 who received the same ART with >95% adherence for at least 6 months were matched to nonobese patients by age, gender, ART, CD4 count, and viral load at baseline. Results: Twenty pairs were included, with an average BMI of 24 kg/m 2 in the nonobese cohort and 35 kg/m 2 in the obese cohort. No difference was observed in the proportion of patients who achieved virologic suppression or the change in CD4 count from baseline to 6 to 12 months. Conclusion: This study revealed no differences in immunologic recovery or virologic suppression between obese and nonobese patients in an adult correctional population.