Einstein (São Paulo) ()

Group A rotavirus gastroenteritis: post-vaccine era, genotypes and zoonotic transmission

  • Adriana Luchs,
  • Maria do Carmo Sampaio Tavares Timenetsky

DOI
https://doi.org/10.1590/S1679-45082016RB3582
Journal volume & issue
Vol. 14, no. 2
pp. 278 – 287

Abstract

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ABSTRACT This article provides a review of immunity, diagnosis, and clinical aspects of rotavirus disease. It also informs about the changes in epidemiology of diarrheal disease and genetic diversity of circulating group A rotavirus strains following the introduction of vaccines. Group A rotavirus is the major pathogen causing gastroenteritis in animals. Its segmented RNA genome can lead to the emergence of new or unusual strains in human populations via interspecies transmission and/or reassortment events.

Keywords