Why do we still have not a vaccine against Chagas disease?

Abstract

This review does not intend to convey detailed experimental or bibliographic data. Instead, it expresses the informal authors’ personal views on topics that range from basic research on antigens and experimental models for Trypanosoma cruzi infection to vaccine prospects and vaccine production. The review also includes general aspects of Chagas’ disease control and international and national policies on the subject. The authors contributed equally to the paper.

Keywords

• Chagas disease control
• prophylactic vaccines
• therapeutic vaccines
• vaccines production
• vaccines evaluation