"Theory of Forms" implies that a genuine version of creatures exists beyond the shapes in this world. Stem celltechnology has adopted developmental cues to mimic real life. However, the functionality of the lab-made cells is farfrom primary ones. Perhaps it is time to switch from analytical to systematic perspective in stem cell science. Thismay be the way to define new horizons based on the systematic perspective and convergence of science in stem cellbiology, bridging the current gap between the shadows of real knowledge in current research and reality in future.