Alkylamides of Acmella oleracea

Yuan-Bin Cheng; Rosa Huang Liu; Meng-Chi Ho; Tung-Ying Wu; Ching-Yeu Chen; I-Wen Lo; Ming-Feng Hou; Shyng-Shiou Yuan; Yang-Chang Wu; Fang-Rong Chang

doi:10.3390/molecules20046970

Molecules (Apr 2015)

Alkylamides of Acmella oleracea

Yuan-Bin Cheng,
Rosa Huang Liu,
Meng-Chi Ho,
Tung-Ying Wu,
Ching-Yeu Chen,
I-Wen Lo,
Ming-Feng Hou,
Shyng-Shiou Yuan,
Yang-Chang Wu,
Fang-Rong Chang

Affiliations

Yuan-Bin Cheng: Graduate Institute of Natural Products, College of Pharmacy, Kaohsiung Medical University, Kaohsiung 807, Taiwan
Rosa Huang Liu: School of Nutrition, College of Health Care and Management, Chung Shan Medical University, Taichung 40201, Taiwan
Meng-Chi Ho: Graduate Institute of Natural Products, College of Pharmacy, Kaohsiung Medical University, Kaohsiung 807, Taiwan
Tung-Ying Wu: Graduate Institute of Natural Products, College of Pharmacy, Kaohsiung Medical University, Kaohsiung 807, Taiwan
Ching-Yeu Chen: Department of Physical Therapy, Tzu-Hui Institute of Technology, Pingtung 926, Taiwan
I-Wen Lo: Graduate Institute of Natural Products, College of Pharmacy, Kaohsiung Medical University, Kaohsiung 807, Taiwan
Ming-Feng Hou: Translational Research Center and Cancer Center, Kaohsiung Medical University Hospital, Kaohsiung 807, Taiwan
Shyng-Shiou Yuan: Translational Research Center and Cancer Center, Kaohsiung Medical University Hospital, Kaohsiung 807, Taiwan
Yang-Chang Wu: Graduate Institute of Natural Products, College of Pharmacy, Kaohsiung Medical University, Kaohsiung 807, Taiwan
Fang-Rong Chang: Graduate Institute of Natural Products, College of Pharmacy, Kaohsiung Medical University, Kaohsiung 807, Taiwan

DOI: https://doi.org/10.3390/molecules20046970
Journal volume & issue: Vol. 20, no. 4
pp. 6970 – 6977

Abstract

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Phytochemical investigation of the flowers of Acmella oleracea had resulted in the isolation of one new alkylamide, (2E,5Z)-N-isobutylundeca-2,5-diene-8,10-diynamide (1), together with four known analogues (2-5). The structures of these compounds were determined by the interpretation of spectroscopic methods, especially NMR technologies (COSY, HSQC, HMBC, and NOESY). In addition, a convenient method for concentrating the alkylamide-rich fraction and analyzing fingerprint profile of A. oleracea was established.

Published in Molecules

ISSN: 1420-3049 (Online)
Publisher: MDPI AG
Country of publisher: Switzerland
LCC subjects: Science: Chemistry: Organic chemistry
Website: http://www.mdpi.com/journal/molecules

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