Multi-Element Fingerprinting Combined with Chemometrics for Identification of Seaweeds and Innovative Risk–Benefit Assessment
Yuansheng Guo,
Tiantian Zuo,
Shuo Gong,
Anzhen Chen,
Hongyu Jin,
Jing Liu,
Qi Wang,
Jingjing Liu,
Shuai Kang,
Ping Li,
Feng Wei,
Shuangcheng Ma
Affiliations
Yuansheng Guo
State Key Laboratory of Drug Regulatory Science, National Institutes for Food and Drug Control, Beijing 100050, China
Tiantian Zuo
State Key Laboratory of Drug Regulatory Science, National Institutes for Food and Drug Control, Beijing 100050, China
Shuo Gong
School of Integrative Medicine, Anhui University of Chinese Medicine, Hefei 230012, China
Anzhen Chen
NMPA Key Laboratory for Quality Research and Evaluation of Traditional Marine Chinese Medicine, Qingdao Institute for Food and Drug Control, Qingdao 266073, China
Hongyu Jin
State Key Laboratory of Drug Regulatory Science, National Institutes for Food and Drug Control, Beijing 100050, China
Jing Liu
State Key Laboratory of Drug Regulatory Science, National Institutes for Food and Drug Control, Beijing 100050, China
Qi Wang
State Key Laboratory of Drug Regulatory Science, National Institutes for Food and Drug Control, Beijing 100050, China
Jingjing Liu
State Key Laboratory of Drug Regulatory Science, National Institutes for Food and Drug Control, Beijing 100050, China
Shuai Kang
State Key Laboratory of Drug Regulatory Science, National Institutes for Food and Drug Control, Beijing 100050, China
Ping Li
School of Pharmacy, China Pharmaceutical University, Nanjing 211198, China
Feng Wei
State Key Laboratory of Drug Regulatory Science, National Institutes for Food and Drug Control, Beijing 100050, China
Shuangcheng Ma
State Key Laboratory of Drug Regulatory Science, National Institutes for Food and Drug Control, Beijing 100050, China
Seaweeds are one of the major marine foods with high values. The diversity of seaweed species significantly impacts their quality and is closely linked to their purity and safety. For the first time, this study established a model to discriminate seaweed species using a multi-element fingerprinting approach for species identification. Twenty-nine elements derived from seaweeds were analyzed. Chemometrics showed that seaweed samples could be well separated by the established multi-element fingerprints, of which Ag, Mn, Sr, and K were the most important variables for discrimination. Furthermore, the present study proposed an innovative risk–benefit assessment strategy for seaweeds that considers both risks and benefits, developing a novel risk–benefit assessment model from both dietary and medicinal perspectives for the first time. Our innovative strategy was well-conceived to accurately and effectively differentiate seaweeds based on species and scientifically evaluate both benefits and risks associated with seaweeds. This strategy is poised to offer invaluable insights into the sustainable growth of the seaweed sector and to bolster public health initiatives, ensuring a robust and forward-looking approach to both industry and healthcare advancements.
