Journal of Arrhythmia (Jan 2006)

Changes of Sympathetic Activity in Patient with Chronic Atrial Fibrillation and Severe Congestive Heart Failure Treated with Biventricular Pacing

  • Kohei Matsushita, MD,
  • Toshiyuki Ishikawa, MD,
  • Shinichi Sumita, MD,
  • Tsukasa Kobayashi, MD,
  • Hideyuki Ogawa, MD,
  • Noriko Inoue, MD,
  • Katsumi Matsumoto, MD,
  • Minoru Taima, MD,
  • Ichirou Nakazawa, MD,
  • Teruyasu Sugano, MD,
  • Tomoaki Ishigami, MD,
  • Kazuaki Uchino, MD,
  • Kazuo Kimura, MD,
  • Satoshi Umemura, MD

DOI
https://doi.org/10.1016/S1880-4276(06)80007-4
Journal volume & issue
Vol. 22, no. 1
pp. 48 – 51

Abstract

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The patient was a 64-year-old man with chronic atrial fibrillation with bradycardia. Left ventricular ejection fraction was 34%. He was treated with biventricular pacing. Heart failure improved from NYHA class III to II. Sympathetic nerve activity (SNA. was recorded during 6 minutes of biventricular (BV), right ventricular apical (RVA. and left ventricular (LV. pacing. SNA was significantly lower during biventricular pacing (49.5 ± 4.0/min. compared with RVA (58.8 ±6:9/min, p = 0.016. and LV (63.3 ± 4.3/min, p = 0.002. pacing. BV pacing improves hemodynamics and decreases SNA compared with RVA or LV pacing.

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