Uterine fibroids in premenopausal women

Abstract

Uterine fibroids are one of the commonest benign pelvic tumours with an estimated incidence of 20–40% in women during their reproductive years. Incidence rates for uterine fibroid diagnoses were highest in premenopausal age. The gynecologists are frequently faced with need for the administration of menopausal hormone therapy (MHT) in this group of patients with the onset of symptoms associated with estrogen deficiency; however, uterine fibroids represent a relative contraindication for the administration of MHT. In the present paper, we point out the need for conservative therapy of uterine fibroids in premenopausal patients to prepare for the administration of MHT. The paper reflects the efficacy of the drug treatment of uterine fibroids using antigestagens (gynestril).

Keywords

• uterine fibroids
• drug treatment
• gynestril
• perimenopausal period
• menopausal hormone therapy (mht)
• hysteroscopy
• ultrasound investigation
• dopplerometry
• uterine volume
• estradiol