Frontiers in Bioengineering and Biotechnology (Nov 2021)

Nanosized Contrast Agents in Ultrasound Molecular Imaging

  • Fengyi Zeng,
  • Fengyi Zeng,
  • Fengyi Zeng,
  • Meng Du,
  • Meng Du,
  • Zhiyi Chen,
  • Zhiyi Chen

DOI
https://doi.org/10.3389/fbioe.2021.758084
Journal volume & issue
Vol. 9

Abstract

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Applying nanosized ultrasound contrast agents (nUCAs) in molecular imaging has received considerable attention. nUCAs have been instrumental in ultrasound molecular imaging to enhance sensitivity, identification, and quantification. nUCAs can achieve high performance in molecular imaging, which was influenced by synthetic formulations and size. This review presents an overview of nUCAs from different synthetic formulations with a discussion on imaging and detection technology. Then we also review the progress of nUCAs in preclinical application and highlight the recent challenges of nUCAs.

Keywords