Histomorphological spectrum of Phyllodes Tumours: A Restrospective Study

Abstract

Introduction: Phyllodes tumours are rare fibroepithelial lesions of breast. Clinical examination, ultrasound, cytology and histopathology are the mainstay of the diagnosis. The present research was undertaken with the aim of studying the clinicopathological features of Phyllodes tumour reported in the past seven years in a Delhi government hospital. Method: A retrospective study of phyllodes tumour was carried out in females from 225 diagnosed cases of breast lesion reported in the pathology department of a government hospital in Delhi during the period of January 2013 to December2019. All the relevant history, findings of clinical examination and investigations performed were assessed from files of the patient. Results: Out of 225 cases of breast lesions reported in the pathology department 8 tumours were reported as phyllodes in the study period. The most common affected age group was 41- 50yrs. 5 (62.5 %) of 8 tumours were benign,2 (25) %) were borderline and only 1 was malignant. The tumour size was 15mm to 200mm. All the 8 cases (100%) presented with breast lump; 3 cases (30%) complained of pain in the lump. 2 cases developed ulceration and Peau D’ orange and in 1 case typical nipple retraction was seen. FNAC was done in 5 patients. No preoperative investigations were done in 2cases. Conclusion: Phyllodes tumour is a rare neoplasm of the breast. Histopathology plays an important role in differentiating it from fibroadenoma. Strict histologic assessment is definitely required for the diagnosis of the PT and for its treatment and management