Nature Communications (Jul 2016)

Protein kinase A modulation of CaV1.4 calcium channels

  • Lingjie Sang,
  • Ivy E. Dick,
  • David T. Yue

DOI
https://doi.org/10.1038/ncomms12239
Journal volume & issue
Vol. 7, no. 1
pp. 1 – 11

Abstract

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Phosphorylation of L-type calcium CaV channels by protein kinase A is essential for several physiological events. Here, the authors show how this kinase regulates CaV1.4 activity, suggesting a general regulatory mechanism for all L-type calcium channels.