پزشکی بالینی ابن سینا (Dec 2000)
The Study of Clinical , Pathological and Laboratory Finding of Forty-Eghit Erythroderma Patients
Abstract
Erythroderma is a term applied to any inflammatory skin disease which affects more than about 90% of the body surface. It is determined by erythema, scaling and pruritus. Clinical , pathological and laboratory finding of erythrodermic patients admitted in dermatologic ward of Sina hospital, Hamadan - Iran , between 1993-1997 (4years)were studied. This retrospective-cross sectional study was done by preparation of the a checklist of necessary information getting from the patients file and then analysis the data with EPI6 software. Among 1107 patients were admitted in the hospital, only 48(4.3%)cases had erythroderma. The most common cause of erythroderma in these patients was preexisting cutaneous disease (56.3%). In this group eczema was most frequent cause of erythroderma ( 27.1% ) and then followed by psoriasis (10%). Other underlying causes of erythroderma in order of frequency were drugs (25%) lymphoma and leukaemias (10.4%) , and idiopathic(8.3%). Antiepileptic drugs were the most frequent drug causes. Age of the most patients was above 40and the ratio of male to female was. Among laboratory finding eosinophilia was reported in more than half of patients (57.7%) with eczema. The most pathologic diagnosis was chronic dermatitis. Clinical finding along with one or more skin biopsis were diagnostic or suggestive of the underlying disease in 69.6% of the cases . Relapse was seen in 11 cases of 34 followed patients , that psoriasis was the most frequent cause of relapse. The prevalence and relapse of erythroderma in this study was more than the other studies which was done in other countries.
