Rosai-Dorfman disease presenting as stridor and hoarseness in a young female patient

Vivianne Kokje, MD, PhD; Claudio De Vito, MD, PhD; Flavia Costa Varela, MD; Yan Monnier, MD, PhD; Nicolas Dulguerov, MD; Minerva Becker, MD; Maxime Mermod, MD, PhD

Radiology Case Reports (Feb 2023)

Rosai-Dorfman disease presenting as stridor and hoarseness in a young female patient

Vivianne Kokje, MD, PhD,
Claudio De Vito, MD, PhD,
Flavia Costa Varela, MD,
Yan Monnier, MD, PhD,
Nicolas Dulguerov, MD,
Minerva Becker, MD,
Maxime Mermod, MD, PhD

Affiliations

Vivianne Kokje, MD, PhD: Department of Otorhinolaryngology—Head and Neck Surgery, Geneva University Hospitals, 4 rue Gabrielle-Perret-Gentil, CH-1211, Geneva, Switzerland
Claudio De Vito, MD, PhD: Division of Clinical Pathology, Diagnostic Department, Geneva University Hospitals, 4 rue Gabrielle-Perret-Gentil, CH-1211, Geneva, Switzerland
Flavia Costa Varela, MD: Department of Otorhinolaryngology—Head and Neck Surgery, Geneva University Hospitals, 4 rue Gabrielle-Perret-Gentil, CH-1211, Geneva, Switzerland; Division of Clinical Pathology, Diagnostic Department, Geneva University Hospitals, 4 rue Gabrielle-Perret-Gentil, CH-1211, Geneva, Switzerland; Service of Radiology, Geneva University Hospitals, 4 rue Gabrielle-Perret-Gentil, CH-1211, Geneva, Switzerland
Yan Monnier, MD, PhD: Department of Otorhinolaryngology—Head and Neck Surgery, Geneva University Hospitals, 4 rue Gabrielle-Perret-Gentil, CH-1211, Geneva, Switzerland
Nicolas Dulguerov, MD: Department of Otorhinolaryngology—Head and Neck Surgery, Geneva University Hospitals, 4 rue Gabrielle-Perret-Gentil, CH-1211, Geneva, Switzerland
Minerva Becker, MD: Service of Radiology, Geneva University Hospitals, 4 rue Gabrielle-Perret-Gentil, CH-1211, Geneva, Switzerland
Maxime Mermod, MD, PhD: Department of Otorhinolaryngology—Head and Neck Surgery, Geneva University Hospitals, 4 rue Gabrielle-Perret-Gentil, CH-1211, Geneva, Switzerland; Corresponding author.

Journal volume & issue: Vol. 18, no. 2
pp. 591 – 595

Abstract

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Rosai-Dorfman disease is a non-Langherans cell histiocytosis typically revealed by lymphadenopathy. Extranodal involvement occurs in 43% and most commonly involves the head and neck, skin, and bones. Few reports have described laryngeal lesions. We report the case of a Rosai-Dorfman disease in a 27-year-old female, presenting as an obstructing transglottic mass. We provide the results of the MRI and PET-scanner examination. As the treatment relies on surgical excision and the diagnosis depends on pathological examination, we also detail the analysis results that followed the surgical resection. This report highlights the necessity to consider Rosai-Dorfman disease as a potential diagnosis in case of a laryngeal submucosal mass.

Published in Radiology Case Reports

ISSN: 1930-0433 (Online)
Publisher: Elsevier
Country of publisher: United States
LCC subjects: Medicine: Medicine (General): Medical physics. Medical radiology. Nuclear medicine
Website: http://www.journals.elsevier.com/radiology-case-reports/

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