BMC Pharmacology and Toxicology (Dec 2018)

Pisa syndrome associated with mirtazapine: a case report

  • Yuji Yamada,
  • Harumasa Takano,
  • Maki Yamada,
  • Naoko Satake,
  • Naotsugu Hirabayashi,
  • Mitsutoshi Okazaki,
  • Kazuyuki Nakagome

DOI
https://doi.org/10.1186/s40360-018-0272-8
Journal volume & issue
Vol. 19, no. 1
pp. 1 – 3

Abstract

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Abstract Background Mirtazapine is a noradrenergic and specific serotonergic antidepressant; its pharmacological profile indicates a low risk for dopaminergic adverse effects. To date, there has been only a single case report of Pisa syndrome associated with mirtazapine. Case presentation The authors report a case involving a 79-year-old woman with bipolar disorder, in whom Pisa syndrome occurred after introduction of mirtazapine, and completely disappeared 3 days after suspension of the drug. Conclusions Aspects of this particular case suggest that Pisa syndrome is a possible side effect of Mirtazapine.

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