Factors predicting successful sperm retrieval in men with nonobstructive Azoospermia: A single center perspective

Abstract

Abstract Predicting successful sperm retrieval is essential in counseling infertile men with Azoospermia. Objectives To assess the predictors of successful sperm extraction in men with nonobstructive Azoospermia. Patients and Methods A retrospective study included all patients with nonobstructive Azoospermia from January 2018 to May 2019. Subdivided into two groups, group I (negative sperm retrieval) and group II (positive sperm retrieval). Results A total of 108 patients with a mean age of 36.8 ± 10 years were included. The rate of successful sperm retrieval was 47.2%. Group I included 57 patients (52.8%) with a mean age of 33.98 ± 6.18, and group II included 51 patients (47.2%) with a mean age of 40.04 ± 12.22 (p = 0.008). Follicular stimulating hormone (FSH) levels were significantly higher in group I (18.55 ± 13 vs. 7.97 ± 7.11; p < 0.004). Similarly, in group I, luteinizing hormone was significantly higher (11.4 ± 7.45 vs. 5.9 ± 4.4; p < 0.001). Age and FSH were the independent predictors of successful micro‐TESE. Additionally, successful pregnancies were 13.7% of patients, 28.6% of which gave rise to living birth. Conclusion Patients' age and serum FSH are independent predictors of successful sperm retrieval for infertile men with nonobstructive Azoospermia; young patients with high FSH levels could have little chance of sperm retrieval.

Keywords

• Azoospermia
• infertility
• microsurgical testicular sperm extraction
• nonobstructive
• sperm retrieval
• testicular sperm extraction