Nature Communications (Jan 2018)

Ultrasensitive reversible chromophore reaction of BODIPY functions as high ratio double turn on probe

  • Dehui Hu,
  • Tao Zhang,
  • Shayu Li,
  • Tianjun Yu,
  • Xiaohui Zhang,
  • Rui Hu,
  • Jiao Feng,
  • Shuangqing Wang,
  • Tongling Liang,
  • Jianming Chen,
  • Lyubov N. Sobenina,
  • Boris A. Trofimov,
  • Yi Li,
  • Jinshi Ma,
  • Guoqiang Yang

DOI
https://doi.org/10.1038/s41467-017-02270-0
Journal volume & issue
Vol. 9, no. 1
pp. 1 – 10

Abstract

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BODIPY dyes, though widely explored, have not been pursued as chromophore reaction based chemical probes. Here, the authors synthesize a meso-naked BODIPY core flanked with two electron-withdrawing groups, which undergoes a reversible change in conjugated structure in the presence of base and functions as a dual signal and ultrahigh turn-on ratio chemical probe.