Open Medicine
(Sep 2021)
Fer exacerbates renal fibrosis and can be targeted by miR-29c-3p
Sun Chen-Min,
Zhang Wen-Yi,
Wang Shu-Yan,
Qian Gang,
Pei Dong-Liang,
Zhang Guang-Ming
Affiliations
Sun Chen-Min
Department of Anesthesiology, Tongren Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200336, China
Zhang Wen-Yi
Department of Anesthesiology, Tongren Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200336, China
Wang Shu-Yan
Department of Anesthesiology, Tongren Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200336, China
Qian Gang
Department of Anesthesiology, Tongren Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200336, China
Pei Dong-Liang
Department of Anesthesiology, Tongren Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200336, China
Zhang Guang-Ming
Department of Anesthesiology, Tongren Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200336, China
DOI
https://doi.org/10.1515/med-2021-0319
Journal volume & issue
Vol. 16,
no. 1
pp.
1378
– 1385
Abstract
Read online
Renal fibrosis (RF) is a common clinical condition leading to irreversible renal function loss. Tyrosine kinase proteins and microRNAs (miRs) are associated with pathogenesis and we aim to investigate the role of Fer and its partner miR(s) in RF.
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