Nutrición Hospitalaria (Oct 2012)
Relación de cortisol sérico con los componentes del síndrome metabólico, ingesta alimentaria y trastorno de ansiedad en niños de 8 a 12 años con obesidad Relationship of serum cortisol and metabolic syndrome components, dietary intakes and anxiety disorder in children at 8 to 12 years of age with obesity
Abstract
Introducción: La obesidad es un trastorno que se asocia con ingesta alimentaria inadecuada y problemas psicológicos y predispone a complicaciones entre ellas el Síndrome Metabólico (SM), el cual ha sido relacionado con el estrés crónico debido a alteraciones en la actividad del eje Hipotálamo-Hipófisis-Adrenal (HHA) mediado por el hipercortisolismo. Objetivo: Determinar la relación del cortisol sérico con los componentes del SM, ingesta alimentaria y trastorno de ansiedad en niños de 8 a 12 años con obesidad. Métodos: 78 niños, 40 con obesidad y 38 con peso adecuado. Se evaluaron indicadores séricos: cortisol, glucosa, colesterol-HDL (c-HDL) y triglicéridos; indicadores antropométricos y clínicos: peso, talla, Índice de Masa Corporal (IMC), circunferencia cintura (CC) y presión arterial (PA); ingesta alimentaria: deficiencia o exceso en el consumo e ingesta de energía y nutrimentos; indicador psicológico: ansiedad. Resultados: Existe relación significativa entre el nivel de cortisol a medida que aumenta el número de componentes del SM en niños con obesidad (p Introduction: Obesity is a disorder associated to an inappropriate food intake and psychological problems predisposing to complications such as metabolic syndrome (MS), which has been related to chronic stress due to hypercortisolism-mediated impairments of the hypothalamushypophysis-adrenal (HHA) axis activity. Objective: To determine the relationship between serum cortisol and MS components, the food intake, and anxiety disorder in 8-12 years old obese children. Methods: 78 children, 40 with obesity and 38 with appropriate weight. The following serum and clinical indicators were assessed: cortisol, glucose, HDL-cholesterol (c-HDL) and triglycerides; anthropometrical and clinical indicators: weight, height, body mass index (BMI), waist circumference (WC) and blood pressure (BP); food intake: deficient or excessive consumption and intake of energy and nutrients; psychological indicator: anxiety. Results: There exists a significant relationship between cortisol level and the number of MS components in obese children (p < 0.05). When assessing the cortisol level against each one of these components, there were no significant differences. When analyzing the total sample, the cortisol level showed a negative relationship with c-HDL (r = -0.228, p = 0.045). We found a significant relationship between the cortisol level and excessive intake of foods of animal origin and sugars and with the subsets of fats and sugars (p < 0.05). There were no significant differences in energy or nutrients intake or anxiety in obese children. Conclusion: There exists a relationship between the cortisol level and the number of MS components as well as with excessive intake of foods of animal origin, sugars, and fats in obese children.
