Jornal Brasileiro de Patologia e Medicina Laboratorial (Jun 2015)

Fatal complication after transsphenoidal surgery of pituitary adenoma: case report

  • Conceição Aparecida Dornelas,
  • Tereza N. A. G. Nogueira,
  • Evandro T. Alves,
  • River A. B. Coêlho

DOI
https://doi.org/10.5935/1676-2444.20150031
Journal volume & issue
Vol. 51, no. 3
pp. 178 – 182

Abstract

Read online

ABSTRACT The objective of this study was to report a rare fatal complication in the postoperative period of transsphenoidal surgery of the pituitary gland (adenoma), with a brief review of the subject. The patient was a 54-year-old white man with acromegaly and severe heart failure, who after microsurgery developed blood pressure instability within 32 hours after the procedure and died. The autopsy revealed: hypertrophy and ventricular dilation with myocarditis, pericarditis and myocardial fibrosis; mesenteric ischemia with transmural coagulation necrosis of the intestinal loops; acute tubular necrosis; and hepatic steatosis. The findings are consistent with cardiogenic shock and abdominal sepsis due to necrosis of the intestinal loops.

Keywords