Light: Science & Applications (Jul 2021)

1700 nm optical coherence microscopy enables minimally invasive, label-free, in vivo optical biopsy deep in the mouse brain

  • Jun Zhu,
  • Hercules Rezende Freitas,
  • Izumi Maezawa,
  • Lee-way Jin,
  • Vivek J. Srinivasan

DOI
https://doi.org/10.1038/s41377-021-00586-7
Journal volume & issue
Vol. 10, no. 1
pp. 1 – 13

Abstract

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1700 nm optical coherence microscopy images neurons and axonal myelination across the mouse neocortex and some sub-cortical regions, based on intrinsic tissue contrast, with minimal invasiveness.