CRITERIA OF TUBERCULOSIS TREATMENT EFFICIENCY IN CHILDREN UNDER CURRENT CONDITIONS

Abstract

The main objective of a phthisiologist following up and treating children and adolescents with local forms of tuberculosis is to achieve complete clinical cure with minimal remaining post-tuberculosis changes. Evaluation of treatment progress is important since it defines not only the duration of chemotherapy and follow-up but it also serves a prognostic criterion of stable clinical cure and prevention of relapse in the future. New criteria for evaluation of tuberculosis activity and clinical cure in children and adolescents were assessed. It was proved that Mantoux test could not be the criterion of the disease activity. While results of the test with tuberculous recombinant allergen (TRA) performed at the moment of clinical cure did not depend on the volume and severity of changes and allowed assessing the activity of the disease with any intensity of specific changes in chest lymph nodes and lung tissue, and TRA test served as a criterion of activity of mycobacterial population in the host.

Keywords

• туберкулез
• дети
• эффективность лечения
• аллерген туберкулезный рекомбинантный
• иммунодиагностика
• диаскинтест