Separation of the natural retinoids by high-pressure liquid chromatography

C A Frolik; T E Tavela; M B Sporn

Journal of Lipid Research (Jan 1978)

Separation of the natural retinoids by high-pressure liquid chromatography

C A Frolik,
T E Tavela,
M B Sporn

Affiliations

C A Frolik: Lung Cancer Branch, National Cancer Institute, Bethesda, MD 20014
T E Tavela: Lung Cancer Branch, National Cancer Institute, Bethesda, MD 20014
M B Sporn: Lung Cancer Branch, National Cancer Institute, Bethesda, MD 20014

Journal volume & issue: Vol. 19, no. 1
pp. 32 – 37

Abstract

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A reverse phase high-pressure liquid chromatography system for rapid separation of various retinoids (vitamin A and its analogs) with little or no degradation is described. This method permits detection of as little as 22 pmol of retinoic acid. The procedure has been applied to the study of retinoic acid metabolism in vitamin A-deficient hamsters.

Published in Journal of Lipid Research

ISSN: 0022-2275 (Print); 1539-7262 (Online)
Publisher: Elsevier
Country of publisher: United States
LCC subjects: Science: Chemistry: Organic chemistry: Biochemistry
Website: https://www.journals.elsevier.com/journal-of-lipid-research

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Abstract

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