Epithelioid hemangioendothelioma of upper lip: A rare entity

Abstract

Epithelioid hemangioendothelioma (EHE) is an uncommon vascular neoplasm intermediating hemangioma and angiosarcoma characterized by the proliferation of epithelioid or histiocytoid endothelial cells with vacuolated cytoplasm and occasional eosinophilic spindle cells. Tumors of intermediate behavior may recur locally and metastasize but with less frequency compared to malignant ones. It rarely affects the oral cavity. Literature review shows only a few cases of this entity in the oral mucosa. Due to its rarity, we report a case of EHE on the upper lip.

Keywords

• Epithelioid hemangioendothelioma
• intraoral
• tumor
• upper lip
• vascular neoplasm