Diabetic retinopathy. Results of international multicentre studies

Abstract

Diabetic retinopathy (DR) is a main cause of blindness throughout the world, with chronic hyperglycemia and arterial hypertension being the keycontributors to the development of this microvascular complication. A few international multicentre studies have recently been conducted to assesseffect of intensive control of glycemia and AH on the development and progress of DR in type 1 and 2 DM patients. Results of DCCT, UKPDS,DIRECT, ADVANCE, and AdREM studies are reviewed.

Keywords

• diabetes mellitus
• diabetic retinopathy
• hyperglycemia
• arterial hypertension
• pathogenesis
• classification