Acta Medica Martiniana (Dec 2016)

Effects of Conventional Mechanical Ventilation Performed by Two Neonatal Ventilators on the Lung Functions of Rabbits with Meconium-Induced Acute Lung Injury

  • Mokra D,
  • Mikolka P,
  • Kosutova P,
  • Kolomaznik M,
  • Jurcek M,
  • Istona P,
  • Matasova K,
  • Zibolen M,
  • Calkovska A

DOI
https://doi.org/10.1515/acm-2016-0012
Journal volume & issue
Vol. 16, no. 3
pp. 5 – 13

Abstract

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Severe meconium aspiration syndrome (MAS) in the neonates often requires a ventilatory support. As a method of choice, a conventional mechanical ventilation with small tidal volumes (VT<6 ml/kg) and appropriate ventilatory pressures is used. The purpose of this study was to assess the short-term effects of the small-volume CMV performed by two neonatal ventilators: Aura V (Chirana Stara Tura a.s., Slovakia) and SLE5000 (SLE Ltd., UK) on the lung functions of rabbits with experimentally-induced MAS and to estimate whether the newly developed neonatal version of the ventilator Aura V is suitable for ventilation of the animals with MAS.

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