Indian Journal of Endocrinology and Metabolism (Jan 2011)

Why are our hypothyroid patients unhappy? Is tissue hypothyroidism the answer?

  • Sanjay Kalra,
  • Sachin Kumar Khandelwal

Journal volume & issue
Vol. 15, no. 6
pp. 95 – 98


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A large number of hypothyroid patients, receiving adequate doses of thyroxine supplementation, continue to complain of dissatisfaction and varied symptoms. This review discuses the concept of tissue hypothyroidism and suggests methods of measuring it, while calling for improvements in the medical management of hypothyroidism.