Romanian Journal of Military Medicine (Dec 2015)
Clostridium difficile – an emerging plague
Abstract
Introduction: Clostridium difficile infection stands nowadays as one of the major emerging health problems still underestimated. Only in 2009 the European Society of Clinical Microbiology and Infection (ESCMID) was able to publish guidelines for this serious disease. Actually the guidelines were updated in 2013 so we can speak of a united action towards the resolution of this healthcare problem. Methods: This is a review article aiming to shed light in various aspects of clostridium difficile infection as clinical presentation, symptoms and signs, therapeutic options and risk factors with a focus on urologic pathology. Conclusions: This type of infection represents a challenge from many points of view like treatment, relapse approach, mortality, morbidity, germ’ s adaptability to treatment and last but not the least the outbreak of different aggressive strains like B1,NAP1 or ribotype 027 toxinotype III.