Losartan therapy in gout patients

Abstract

Aim. To study losartan effectiveness and safety in patients with gout and arterial hypertension (AH).Material and methods. In total, 30 patients not having goat attack were examined (mean age 49,8+10,5 years, disease duration - 6,5 (3,0;16) years). For 8 weeks, antihypertensive and uricosuric activity of losartan, as well as its adverse effects, were examined.Results. Blood pressure normalized in 63% of the participants, serum uric acid level decreased by 9%, and uricosuria increased by 14%. No adverse effects or arthritic signs were registered.Conclusion. Losartan could be recommended for treating AH in gout patients.

Keywords

• gout
• hyperuricemia
• arterial hypertension
• losartan