Drug Design, Development and Therapy (Sep 2023)

Macro, Micro, and Nano-Inspired Bioactive Polymeric Biomaterials in Therapeutic, and Regenerative Orofacial Applications

  • Atia GA,
  • Shalaby HK,
  • Roomi AB,
  • Ghobashy MM,
  • Attia HA,
  • Mohamed SZ,
  • Abdeen A,
  • Abdo M,
  • Fericean L,
  • Bănățean Dunea I,
  • Atwa AM,
  • Hasan T,
  • Mady W,
  • Abdelkader A,
  • Ali SA,
  • Habotta OA,
  • Azouz RA,
  • Malhat F,
  • Shukry M,
  • Foda T,
  • Dinu S

Journal volume & issue
Vol. Volume 17
pp. 2985 – 3021

Abstract

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Gamal A Atia,1 Hany K Shalaby,2 Ali B Roomi,3,4 Mohamed M Ghobashy,5 Hager A Attia,6 Sara Z Mohamed,7 Ahmed Abdeen,8 Mohamed Abdo,9,10 Liana Fericean,11 Ioan Bănățean Dunea,11 Ahmed M Atwa,12 Tabinda Hasan,13 Wessam Mady,14 Afaf Abdelkader,15 Susan A Ali,16 Ola A Habotta,17 Rehab A Azouz,18 Farag Malhat,19 Mustafa Shukry,20 Tarek Foda,21 Stefania Dinu22 1Department of Oral Medicine, Periodontology, and Diagnosis, Faculty of Dentistry, Suez Canal University, Ismailia, Egypt; 2Department of Oral Medicine, Periodontology and Oral Diagnosis, Faculty of Dentistry, Suez University, Suez, Egypt; 3Department of Quality Assurance, University of Thi-Qar, Thi-Qar, Iraq; 4Department of Medical Laboratory, College of Health and Medical Technology, National University of Science and Technology, Thi-Qar, Iraq; 5Radiation Research of Polymer Chemistry Department, National Center for Radiation Research and Technology (NCRRT), Atomic Energy Authority, Cairo, Egypt; 6Department of Molecular Biology and Chemistry, Faculty of Science, Alexandria University, Alexandria, Egypt; 7Department of Removable Prosthodontics, Faculty of Dentistry, Suez Canal University, Ismailia, Egypt; 8Department of Forensic Medicine and Toxicology, Faculty of Veterinary Medicine, Benha University, Toukh, Egypt; 9Department of Animal Histology and Anatomy, School of Veterinary Medicine, Badr University in Cairo (BUC), Badr City, Egypt; 10Department of Anatomy and Embryology, Faculty of Veterinary Medicine, University of Sadat City, Sadat, Egypt; 11Department of Biology and Plant Protection, Faculty of Agriculture. University of Life Sciences “King Michael I” from Timișoara, Timișoara, Romania; 12Department of Pharmacology and Toxicology, Faculty of Pharmacy, Egyptian Russian University, Cairo, Egypt; 13Department of Basic Sciences, College of Medicine, Princess Nourah bint Abdulrahman University, Riyadh, Saudi Arabia; 14Center of Excellence in Genomic Medicine Research, King Abdulaziz University, Jeddah, Saudi Arabia; 15Department of Forensic Medicine and Clinical Toxicology, Faculty of Medicine, Benha University, Benha, Egypt; 16Department of Radiodiagnosis, Faculty of Medicine, Ain Shams University, Abbassia, 1181, Egypt; 17Department of Forensic Medicine and Toxicology, Faculty of Veterinary Medicine, Mansoura University, Mansoura, Egypt; 18Department of Forensic Medicine and Toxicology, Faculty of Veterinary Medicine, Cairo University, Giza, Egypt; 19Department of Pesticide Residues and Environmental Pollution, Central Agricultural Pesticide Laboratory, Agricultural Research Center, Giza, Egypt; 20Department of Physiology, Faculty of Veterinary Medicine, Kafrelsheikh University, Kafrelsheikh, Egypt; 21Oral Health Sciences Department, Temple University’s Kornberg School of Dentistry, Philadelphia, PA, USA; 22Department of Pedodontics, Faculty of Dental Medicine, Victor Babes University of Medicine and Pharmacy Timisoara, Timisoara, 300041, RomaniaCorrespondence: Gamal A Atia, Department of Oral Medicine, Periodontology, and Diagnosis, Faculty of Dentistry, Suez Canal University, Ismailia, 41522, Egypt, Tel +201026961611, Email [email protected] Liana Fericean. Department of Biology and Plant Protection, Faculty of Agriculture, University of Life Sciences “King Michael I” from Timișoara, Calea Aradului 119, CUI 3487181, Romania, Tel +40723085385, Email [email protected]: Introducing dental polymers has accelerated biotechnological research, advancing tissue engineering, biomaterials development, and drug delivery. Polymers have been utilized effectively in dentistry to build dentures and orthodontic equipment and are key components in the composition of numerous restorative materials. Furthermore, dental polymers have the potential to be employed for medication administration and tissue regeneration. To analyze the influence of polymer-based investigations on practical medical trials, it is required to evaluate the research undertaken in this sector. The present review aims to gather evidence on polymer applications in dental, oral, and maxillofacial reconstruction.Keywords: polymers, regeneration, oral, dental, maxillofacial

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