Macromolecular Materials and Engineering (Aug 2024)

Electrospun PCL‐Based Materials for Health‐Care Applications: An Overview

  • Teboho Clement Mokhena,
  • Mandla Brian Chabalala,
  • Sivuyisiwe Mapukata,
  • Asanda Mtibe,
  • Lerato Hlekelele,
  • Zamani Cele,
  • Mokgaotsa Jonas Mochane,
  • Bulelwa Ntsendwana,
  • Toitoi Amos Nhlapo,
  • Teboho Patrick Mokoena,
  • Mokae Fanuel Bambo,
  • Kgabo Phillemon Matabola,
  • Suprakas Sinha Ray,
  • Emmanuel Rotimi Sadiku,
  • Katekani Shingange

DOI
https://doi.org/10.1002/mame.202300388
Journal volume & issue
Vol. 309, no. 8
pp. n/a – n/a

Abstract

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Abstract Polycaprolactone (PCL) is one of the durable polymers with potential in a plethora of healthcare applications. Its biological properties, degradability, chemical properties, and mechanical properties can further be modified to manufacture desired products for modern biomedical applications. Electrospinning of PCL offers the opportunity to design treatment materials that resemble human tissues and facilitate regeneration at the target site. The resultant materials can also be modified by loading other active functional materials to broaden their applications. Herein, the recent advances in the preparation and modification of PCL‐based materials for healthcare applications are elucidated. The challenges and future trends for its application in modern biomedical applications are also outlined.

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