Frontiers in Neuroscience (Jun 2017)

The Electrically Evoked Compound Action Potential: From Laboratory to Clinic

  • Shuman He,
  • Holly F. B. Teagle,
  • Craig A. Buchman

DOI
https://doi.org/10.3389/fnins.2017.00339
Journal volume & issue
Vol. 11

Abstract

Read online

The electrically evoked compound action potential (eCAP) represents the synchronous firing of a population of electrically stimulated auditory nerve fibers. It can be directly recorded on a surgically exposed nerve trunk in animals or from an intra-cochlear electrode of a cochlear implant. In the past two decades, the eCAP has been widely recorded in both animals and clinical patient populations using different testing paradigms. This paper provides an overview of recording methodologies and response characteristics of the eCAP, as well as its potential applications in research and clinical situations. Relevant studies are reviewed and implications for clinicians are discussed.

Keywords