BMC Bioinformatics (Dec 2006)

A novel approach to phylogenetic tree construction using stochastic optimization and clustering

  • Pan Yi,
  • Chen Yixin,
  • Qin Ling,
  • Chen Ling

DOI
https://doi.org/10.1186/1471-2105-7-s4-s24
Journal volume & issue
Vol. 7, no. Suppl 4
p. S24

Abstract

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Abstract Background The problem of inferring the evolutionary history and constructing the phylogenetic tree with high performance has become one of the major problems in computational biology. Results A new phylogenetic tree construction method from a given set of objects (proteins, species, etc.) is presented. As an extension of ant colony optimization, this method proposes an adaptive phylogenetic clustering algorithm based on a digraph to find a tree structure that defines the ancestral relationships among the given objects. Conclusion Our phylogenetic tree construction method is tested to compare its results with that of the genetic algorithm (GA). Experimental results show that our algorithm converges much faster and also achieves higher quality than GA.