Case Reports in Oncology (Dec 2023)

Pulmonary Mucosa-Associated Lymphoid Tissue Lymphoma Treated with Radiation Therapy: A Case Report and Review of the Literature

  • Paul Armstrong,
  • Patrick Hayden,
  • Michael Jeffers,
  • Lisa Fitzpatrick,
  • Aoife Mcknight,
  • John Armstrong

DOI
https://doi.org/10.1159/000534802
Journal volume & issue
Vol. 16, no. 1
pp. 1528 – 1535

Abstract

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Introduction: Mucosa-associated lymphoid tissue lymphoma (MALT lymphoma or MALToma) is a prevalent type of primary pulmonary lymphoma. Typically, the primary therapeutic approaches involve surgery or chemotherapy, although there have been instances of radiation therapy being employed. Case Report: We present a case of pulmonary MALToma that exhibited progression despite rituximab therapy. Subsequently, the patient demonstrated a positive response to radiation therapy. Conclusion: This case highlights the potential efficacy of radiation therapy as a treatment option for pulmonary MALToma, especially in cases where other conventional treatments like rituximab have proven ineffective. Further research and studies are warranted to better understand the role of radiation therapy in managing pulmonary MALToma and to determine optimal treatment strategies for patients with this condition.

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