Rare Tumors (Dec 2020)

Molecular analysis of a rare case of low-grade primary peritoneal serous carcinoma in a male

  • Vladislav V Makarenko,
  • Dina Kandil,
  • Ediz F Cosar,
  • Lloyd Hutchinson,
  • Ashraf Khan

DOI
https://doi.org/10.1177/2036361320979219
Journal volume & issue
Vol. 12

Abstract

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Primary peritoneal serous carcinomas (PPSC) are exceedingly rare in male patients. Only a few cases were reported, and mostly with the limited immunophenotypical characterization. No molecular analysis of PPSC in males has been previously performed. We here describe another case of PPSC in a male patient. A comprehensive molecular analysis of the tumor revealed SF3B1 gene mutation as a possible driver.