Pathogens (Aug 2021)

Natural Products and Their Potential Anti-HAV Activity

  • Agnieszka Jama-Kmiecik,
  • Jolanta Sarowska,
  • Dorota Wojnicz,
  • Irena Choroszy-Król,
  • Magdalena Frej-Mądrzak

DOI
https://doi.org/10.3390/pathogens10091095
Journal volume & issue
Vol. 10, no. 9
p. 1095

Abstract

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The role of purified natural products in the prevention and treatment of countless diseases of bacterial, fungal, and viral origin cannot be overestimated. New antiviral drugs have been obtained from natural sources and transformed into preparations for prophylactic and therapeutic purposes. Flavonoids, polyphenols, saponins, proanthocyanins, polysaccharides, organic acids, proteins, polypeptides, and essential oils derived from plants, animals, or microorganisms can control and combat foodborne viral infections, including hepatitis A. The components of essential oils are characterized by numerous therapeutic and antioxidant properties and exhibit a broad spectrum of antimicrobial and antiviral activity. Due to these properties, they can be used to preserve meat, fruit, vegetables, and their products. Over the past two decades, much effort has been made to identify natural products, mostly of plant origin, to combat foodborne viruses. Natural plant extracts have several potential uses, not limited to increasing the safety of food products and improving their quality, but also as natural antiviral agents.

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