A unique case of epithelioid schwannoma; rare soft tissue tumor

Abstract

Epithelioid schwannoma is a rare histological subtype of schwannoma that can cause diagnostic challenges. Most reported cases in the literature were located predominantly in the dermis and subcutaneous tissue of the extremities and trunk. Only few case reports document epithelioid schwannoma arising in deep soft tissue. Herein we report an interesting case of a benign epithelioid schwannoma found in one thigh of an otherwise healthy 30-year-old man. This tumor was benign, as is indicated by its long pre-surgery clinical history, encapsulation, bland cellular morphology, absence of necrosis or atypical mitotic figures, and recurrence-free survival. This entity should be kept in the differential diagnosis to avoid misdiagnosing it as a malignant soft tissue tumor. Keywords: Epithelioid schwannoma, Benign peripheral nerve sheath tumor, Epithelioid nerve sheath tumor