Pasteur effect in leukocyte energy metabolism of patients with mild, moderate, and severe COVID-19

Ortatatli Mesut; Sengul Goksemin Fatma; Fatsa Tugba; Sertoglu Erdim; Boyunaga Hakan; Kenar Levent

doi:10.1515/tjb-2024-0301

Türk Biyokimya Dergisi (Mar 2025)

Pasteur effect in leukocyte energy metabolism of patients with mild, moderate, and severe COVID-19

Ortatatli Mesut,
Sengul Goksemin Fatma,
Fatsa Tugba,
Sertoglu Erdim,
Boyunaga Hakan,
Kenar Levent

Affiliations

Ortatatli Mesut: Department of Medical CBRN Defence, University of Health Sciences, Ankara, Türkiye
Sengul Goksemin Fatma: Department of Medical Biochemistry, Faculty of Medicine, Ankara Medipol University, Altındag, Türkiye
Fatsa Tugba: Molecular Application and Research Unit of R&D Laboratory, University of Health Sciences, Ankara, Türkiye
Sertoglu Erdim: Department of Medical Biochemistry, Faculty of Medicine, University of Health Sciences, Ankara, Türkiye
Boyunaga Hakan: Department of Medical Biochemistry, Faculty of Medicine, Ankara Medipol University, Altındag, Türkiye
Kenar Levent: Department of Medical CBRN Defence, University of Health Sciences, Ankara, Türkiye

DOI: https://doi.org/10.1515/tjb-2024-0301
Journal volume & issue: Vol. 50, no. 3
pp. 395 – 402

Abstract

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The Pasteur effect in cellular energy metabolism is defined as the switch to anaerobic glycolysis due to alterations in ambient oxygen concentration or inhibition of the electron transport chain (ETC) and oxidative phosphorylation. This study aimed to determine the effect of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) infection on the energy metabolism of leukocytes among Coronavirus Disease 2019 (COVID-19) patients at various stages.

Published in Türk Biyokimya Dergisi

ISSN: 1303-829X (Online)
Publisher: De Gruyter
Country of publisher: Germany
LCC subjects: Science: Chemistry: Organic chemistry: Biochemistry
Website: https://www.degruyter.com/journal/key/tjb/html

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