Nature Communications (Mar 2020)

Fiber reinforced GelMA hydrogel to induce the regeneration of corneal stroma

  • Bin Kong,
  • Yun Chen,
  • Rui Liu,
  • Xi Liu,
  • Changyong Liu,
  • Zengwu Shao,
  • Liming Xiong,
  • Xianning Liu,
  • Wei Sun,
  • Shengli Mi

DOI
https://doi.org/10.1038/s41467-020-14887-9
Journal volume & issue
Vol. 11, no. 1
pp. 1 – 12

Abstract

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Regeneration of corneal stroma has been a challenge due to its sophisticated structure and the easy transformation of the keratocyte. Here, the authors use a hydrogel reinforced with orthogonally aligned fibres and serum free medium to maintain keratocyte phenotype for the in vivo stromal regeneration.