A rare fatal case of adenovirus serotype 4 associated acute disseminated encephalomyelitis in an adult: A case report
Zahra Qamar,
Catherine M. Tucker,
Lawrence C. Kenyon,
Tricia L. Royer
Affiliations
Zahra Qamar
Department of Medicine, Division of Infectious Diseases, Thomas Jefferson University Hospital, 1015 Chestnut Street, Suite 1020, Philadelphia, PA, 19107, United States; Corresponding author at: 1015 Chestnut Street, Suite 1214, Philadelphia, PA, 19103, United States.
Catherine M. Tucker
Department of Pathology, Anatomy and Cell Biology, Thomas Jefferson University Hospital, 280 Main Building, 132 S. 10th Street, Philadelphia, PA, 19107, United States; Corresponding author at: 280 Main Building, 132 S. 10th Street, Philadelphia, PA, 19107, United States.
Lawrence C. Kenyon
Department of Pathology, Anatomy and Cell Biology, Thomas Jefferson University Hospital, 280 Main Building, 132 S. 10th Street, Philadelphia, PA, 19107, United States
Tricia L. Royer
Department of Medicine, Division of Infectious Diseases, Thomas Jefferson University Hospital, 1015 Chestnut Street, Suite 1020, Philadelphia, PA, 19107, United States
Acute disseminated encephalomyelitis (ADEM) is an autoimmune demyelinating disease directed against the myelin sheath of the central nervous system that typically presents 1–4 weeks after an infection or vaccination, most commonly in children. We describe a case of a young female who presented with rapidly progressive mental deterioration and died secondary to ADEM following an adenovirus upper respiratory tract infection.
