Extrafollicular proliferation of B‐blasts: Morphologic correlate to Spikevax‐induced lymphadenopathy

Abstract

Abstract A 30‐year‐old male developed a PET‐positive left‐sided cervical lymphadenopathy that was suspected representing metastasis of a known right‐sided papillary thyroid cancer. First‐dose‐application of Spikevax three weeks ago was neither reflected, nor reported to the pathologists. Diagnostic lymphadenectomy was performed showing extrafollicular proliferation of B‐blasts, likely attributable to the vaccine application.

Keywords

• COVID‐19
• extrafollicular proliferation of B‐blasts
• lymphadenopathy
• mRNA vaccine
• Spikevax