Expanding the Repertoire of Dielectric Fractional Models: A Comprehensive Development and Functional Applications to Predict Metabolic Alterations in Experimentally-Inaccessible Cells or Tissues
Francesco Farsaci,
Ester Tellone,
Antonio Galtieri,
Silvana Ficarra
Affiliations
Francesco Farsaci
Institute for Chemical and Physical Processes (IPCF-C.N.R.), Via Ferdinando Stagno d’Alcontres 37, Faro Superiore, 98158 Messina, Italy
Ester Tellone
Department of Chemical, Biological, Pharmaceutical and Environmental Sciences, University of Messina, Viale Ferdinando Stagno d’Alcontres 31, 98166 Messina, Italy
Antonio Galtieri
Department of Chemical, Biological, Pharmaceutical and Environmental Sciences, University of Messina, Viale Ferdinando Stagno d’Alcontres 31, 98166 Messina, Italy
Silvana Ficarra
Department of Chemical, Biological, Pharmaceutical and Environmental Sciences, University of Messina, Viale Ferdinando Stagno d’Alcontres 31, 98166 Messina, Italy
In this paper, we present the theoretical approach developed by us in the network of dielectric fractional theories. In particular, we mention the general aspects of the non-equilibrium thermodynamics, and after an introduction to the interaction between biological tissues and electrical fields, we highlight the role of phenomenological and state equations; therefore, we recall a general formulation on linear response theory. In Section 6, we introduce the classical fractional model. All of this is essential to show the role and the importance of fractional models in the context of thermodynamic dielectric investigations (of living or inert matter), giving a complete vision of the fractional approach. In Section 7 and Section 8, we introduce our new fractional model derived from non-equilibrium thermodynamic considerations.