Beilstein Journal of Organic Chemistry (May 2018)
Synthesis of pyrazolopyrimidinones using a “one-pot” approach under microwave irradiation
Abstract
A simple one-pot method for the microwave-assisted synthesis of substituted pyrazolo[1,5-a]pyrimidinones, a core scaffold in many bioactive and pharmaceutically relevant compounds, has been established. A variety of substituents was tolerated at the 2 and 5 positions, including functionalized aryls, heterocycles, and alkyl groups.
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