CHEMILUMINESCENT ACTIVITY OF NEUTROPHILS IN PATIENTS WITH ISCHEMIC HEART DISEASE WITH DIFFERENT SENSITIVITY TO ACETYLSYLICYLIC ACID

Abstract

In order to study the characteristics of neutrophil chemiluminescent activity in sensitive and acetylsalicylic acid (ASK) resistant patients with ischemic heart disease (IHD), 53 patients with IHD were examined. All patients were divided into groups sensitive and resistant to ASA. After that, the functional activity of neutrophils was investigated. As a result, in patients with IHD, a slow rate of development of a “respiratory explosion” in neutrophils is detected. A decrease in the activation index was found in patients resistant to ASA.

Keywords

• ишемическая болезнь сердца
• ацетилсалициловая кислота
• нейтрофилы
• хемилюминесцентная активность