The main protease of SARS-CoV-2 downregulates innate immunity via a translational repression

• Weifeng Liang,
• Ming Gu,
• Lingxiang Zhu,
• Ziqi Yan,
• Dominik Schenten,
• Shelby Herrick,
• Hongmin Li,
• Subodh Kumar Samrat,
• Jiapeng Zhu,
• Yin Chen

Affiliations

Weifeng Liang

School of Medicine & Holistic Integrative Medicine, Nanjing University of Chinese Medicine

Ming Gu

School of Medicine & Holistic Integrative Medicine, Nanjing University of Chinese Medicine

Lingxiang Zhu

Department of Pharmacology and Toxicology, School of Pharmacy, The University of Arizona

Ziqi Yan

Department of Pharmacology and Toxicology, School of Pharmacy, The University of Arizona

Dominik Schenten

Department of Immunology, School of Medicine, The University of Arizona

Shelby Herrick

Department of Pharmacology and Toxicology, School of Pharmacy, The University of Arizona

Hongmin Li

Department of Pharmacology and Toxicology, School of Pharmacy, The University of Arizona

Subodh Kumar Samrat

Department of Pharmacology and Toxicology, School of Pharmacy, The University of Arizona

Jiapeng Zhu

School of Medicine & Holistic Integrative Medicine, Nanjing University of Chinese Medicine

Yin Chen

Department of Pharmacology and Toxicology, School of Pharmacy, The University of Arizona