Memorias do Instituto Oswaldo Cruz ()

Characterisation of ocular involvement in an experimental model of neuroschistosomiasis mansoni

  • Thiago Andre Alves Fidelis,
  • Geraldo Brasileiro-Filho,
  • Helena Hollanda Santos,
  • Daniel Vitor Vasconcelos-Santos,
  • Patricia M Parreiras,
  • Paulo Marcos Z Coelho,
  • Neusa Araujo,
  • Marco Vinicius Chaud,
  • José Roberto Lambertucci

DOI
https://doi.org/10.1590/0074-02760190029
Journal volume & issue
Vol. 114

Abstract

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The Global Burden of Disease Study 2010 listed schistosomiasis among the leading 100 causes of death in Brazil, responsible for 3.6% of the estimated total of deaths globally. Eye and adnexa are very rarely affected by schistosomiasis mansoni, with limited documentation of ocular pathology in this setting. This short communication reports ocular histolopathological findings in a murine model of neuroschistosomiasis mansoni. Lesions were found in the bulbar conjunctiva, lacrimal gland, choroid and corneoscleral limbus.

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