Nature Communications (Aug 2018)

Linear mapping approximation of gene regulatory networks with stochastic dynamics

  • Zhixing Cao,
  • Ramon Grima

DOI
https://doi.org/10.1038/s41467-018-05822-0
Journal volume & issue
Vol. 9, no. 1
pp. 1 – 15

Abstract

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The intractability of most stochastic models of gene regulatory networks (GRNs) limits their utility. Here, the authors present a linear-mapping approximation mapping models onto simpler ones, giving approximate but accurate analytic or semi- analytic solutions for a wide range of model GRNs.