One of the most important and necessary aim during breeding project realization is to develop varieties, cultivars and F1 hybrids possessing the resistance to pathogens and pests. Joint efforts of plant breeders and immunologists of All-Russian Research Institute of Vegetable Breeding and Seed Production (VNIISSOK) have been resulting in development new varieties, F1 hybrids with combined resistance to Crucifer flea and other leaf pests.