Emerging Infectious Diseases (Jun 2023)

Isolated Ocular Mpox without Skin Lesions, United States

  • Minh T. Nguyen,
  • Akshay Mentreddy,
  • Julie Schallhorn,
  • Matilda Chan,
  • Su Aung,
  • Sarah B. Doernberg,
  • Jennifer Babik,
  • Kevin Miles,
  • Katherine Yang,
  • Emily Lydon,
  • Daniel J. Minter,
  • John Gonzales,
  • Jessica Shantha,
  • Thuy Doan,
  • Gerami D. Seitzman

DOI
https://doi.org/10.3201/eid2906.230032
Journal volume & issue
Vol. 29, no. 6
pp. 1285 – 1288

Abstract

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We report a case of a 53-year-old HIV-negative patient in San Francisco, California, USA, with no classic mpox prodromal symptoms or skin lesions who experienced fulminant, vision-threatening scleritis, keratitis, and uveitis. Deep sequence analysis identified monkeypox virus RNA in the aqueous humor. We confirmed the virus on the cornea and sclera by PCR.

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