Communications Biology (Jun 2021)

I(nsp1)ecting SARS-CoV-2–ribosome interactions

  • Matthieu Simeoni,
  • Théo Cavinato,
  • Daniel Rodriguez,
  • David Gatfield

DOI
https://doi.org/10.1038/s42003-021-02265-0
Journal volume & issue
Vol. 4, no. 1
pp. 1 – 5

Abstract

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Simeoni et al discuss how recent structural work has improved our understanding of SARS-CoV-2 Nsp1-mediated translation inhibition and how Nsp1 inhibition could impact host immune responses and suppress viral replication.