EPICARDIAL ADIPOSE TISSUE: ANATOMICAL, PHYSIOLOGICAL AND PATHOPHYSIOLOGICAL PROPERTIES AND FUNCTIONS

Abstract

Epicardial adipose tissue (EAT) is of great interest to researchers, since its anatomical, physiological and pathophysiological properties are closely related not only to cardiac pathology, but also to other body systems (endocrine, metabolic). In pediatric practice, the study of EAT, especially in patients with obesity and metabolic syndrome, is at an early stage, which significantly contributes to the difficulty of predicting the development of remote cardiovascular and metabolic complications in adulthood. Adipokines such as visfatin, resistin, adrenomedulin, apelin and others secreted in EAT participate in the regulation of metabolic processes and lead to the formation of such conditions as insulin resistance, arterial hypertension, myocardial remodeling, atherothrombotic vascular changes.

Keywords

• ожирение
• эпикардиальная жировая ткань
• адипокины
• сахарный диабет
• инсулинорезистентность